DCP-LA
DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis.
| Trivial name | FR236924 |
| Catalog Number | E7498 |
| Molecular Formula | C21H27FO6 |
| CAS# | 28399-31-7 |
| Inchi | InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1 |
| Inchi Key | GFNANZIMVAIWHM-OBYCQNJPSA-N |
| SMILES | CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/dcp-la.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7498-dcp-la-chemical-structure-tube.png |