JNT-517
JNT-517 is a selective and orally bioavailable inhibitor of SLC6A19, with an IC50 of 47 nM against human SLC6A19 in the isoleucine transport assay. JNT-517 treatment increases urinary excretion of phenylalanine (Phe) in a mouse model of phenylketonuria (PKU), thereby reducing plasma Phe levels.
| Catalog Number | E1920 |
| CAS# | 2837993-05-0 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/jnt-517.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1920-JNT-517-chemical-structure.png |