TYM-3-98
TYM-3-98 is a selective inhibitor of PI3Kδ with an IC50 of 7.1 nM. It blocks the PI3Kδ/AKT signaling pathway, induces apoptosis in B-cell lymphomas, and effectively suppresses xenograft tumor growth in vivo.
| Catalog Number | E4765 |
| Molecular Formula | C22H24BrFN4O2 |
| CAS# | 2820244-59-3 |
| Inchi | InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) |
| Inchi Key | UHTHHESEBZOYNR-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tym-3-98.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4765-TYM-3-98-chemical-structure.png |