KH-4-43 | MedChemExpress (MCE)

KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4’s core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 μM, respectively[1].

Trivial name KH-4-43
Catalog Number HY-148602
Research Area Cancer
CAS# 2813310-07-3
Purity 99.99%
SMILES O=C1C2=CC=C(C(O)=C2OC(C(F)(F)F)=C1C3=CN(C4=CC=C(C=C4)Cl)N=C3)O
PubChem Chemical Structure ID 164603779
Size 10 mg
Supplier Page https://www.medchemexpress.com/kh-4-43.html