AMG-193

AMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 μM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.

Price Not Available 5mg AMG-193 Supplier Page

Catalog Number	E1600
Molecular Formula	C22H22N6O
CAS#	2790567-82-5
SMILES	NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCCNC5
Size	5mg
Supplier Page	http://www.selleckchem.com/products/amg-193.html
Additional Information	https://file.selleck.cn/downloads/struct/E1600-AMG-193-chemical-structure.png