PROTAC AR-V7 degrader-1| ChemScene
PROTAC AR-V7 degrader-1 (Compound 6) is a potent, orally?bioavailable and selective AR-V7 degrader with the DC50?of 0.32?μM by recruiting VHL E3?ligase?to Androgen receptor?(AR) DNA binding?domain (DBD) binder. PROTAC AR-V7 degrader-1 exhibits activity against 22Rv1 cell-line expressing AR-V7 with the EC50 of 0.88 μM.
| Trivial name | PROTAC AR-V7 degrader-1 |
| Catalog Number | CS-0374913 |
| Molecular Formula | 789.02 |
| CAS# | 2767440-24-2 |
| Purity | >98% |
| Condensed Formula | C41H52N6O6S2 |
| Size | 100mg |
| Supplier Page | www.chemscene.com/2767440-24-2.html |