JNJ-28583113

JNJ-28583113 is a potent, brain-penetrant antagonist of TRPM2 with an IC50 of 126 nM that protects cells from oxidative stress-induced death and morphological changes. It also inhibits microglial cytokine release in response to pro-inflammatory stimuli and promotes GSK3α/β phosphorylation.

Price Not Available 25mg JNJ-28583113 Supplier Page

Catalog Number	E5813
Molecular Formula	C29H38O4
CAS#	2765255-93-2
Inchi	InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
Inchi Key	KQJSQWZMSAGSHN-JJWQIEBTSA-N
SMILES	CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
Size	25mg
Supplier Page	http://www.selleckchem.com/products/jnj-28583113.html
Additional Information	https://file.selleck.cn/downloads/struct/E5813-JNJ-28583113-chemical-structure.png