GRL-190-21 | MedChemExpress (MCE)

GRL-190-21 (compound 5e) is an inhibitor for SARS-Cov-2-Mpro with a Ki of 0.04 nM and exhibits antiviral activity in VeroE6 cells with EC50 of 0.26 μM. GRL-190-21 reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without significant toxicity[1].

Trivial name GRL-190-21
Catalog Number HY-162229
Research Area Infection
CAS# 2755957-14-1
Purity ≥98.0%
SMILES O=C(N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C[C@@]2([H])C(NCCC2)=O)C#N)=O)[C@]3([H])[C@](C3(C)C)([H])C1)=O)C(F)(F)F
Size 1 mg
Supplier Page https://www.medchemexpress.com/grl-190-21.html