LE 300
LE 300 is a potent and selective dopamine D1-like receptor antagonist with Kis of 1.9 nM and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively. LE 300 is an antagonist of the 5-HT2A receptor with a pA2 of 8.32 in a rat tail artery assay.
| Catalog Number | E7705 |
| Molecular Formula | C8H15N7O2S3 |
| CAS# | 274694-98-3 |
| Inchi | InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) |
| Inchi Key | XUFQPHANEAPEMJ-UHFFFAOYSA-N |
| SMILES | C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/le-300.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7705-le-300-chemical-structure-tube.png |