Zidesamtinib | MedChemExpress (MCE)
Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer[1].
| Trivial name | Zidesamtinib |
| Catalog Number | HY-152292 |
| Alternative Name(s) | NVL-520 |
| Research Area | Cancer |
| CAS# | 2739829-00-4 |
| Purity | 99.55% |
| SMILES | CCN1C2=C(C=N1)CC3=NN(C)N=C3C4=CC=C(F)C=C4[C@H](OC5=C(N)N=CC2=C5)C |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/nvl-520.html |