PF-07265028
PF-07265028 is a potent and selective inhibitor of hematopoietic progenitor kinase 1 (HPK1/MAP4K1) with a Ki of <0.05 nM, and exhibits potent cellular activity, with a pSLP76 IC50 of 17 nM.
Catalog Number | E5816 |
Molecular Formula | C20H27N5O2 |
CAS# | 2736458-30-1 |
Inchi | InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26) |
Inchi Key | RRGUKTPIGVIEKM-UHFFFAOYSA-N |
SMILES | C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4 |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pf-07265028.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5816-PF-07265028-chemical-structure.png |