Tagtociclib hydrate | MedChemExpress (MCE)

PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).

Trivial name Tagtociclib hydrate
Catalog Number HY-137894A
Alternative Name(s) PF-07104091 hydrate
Research Area Cancer
CAS# 2733575-91-0
Purity 100.0%
SMILES O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]
Size 10 mM * 1 mL
Supplier Page https://www.medchemexpress.com/pf-07104091-hydrate.html