TSLP binder-1 | MedChemExpress (MCE)

TSLP binder-1 (compound 46) is a bicyclic peptide, which binds to thymic stromal lymphopoietin (TSLP) at the site used by IL-7Rα subunit, shows high affinity for TSLP, with KD of 13 nM. TSLP binder-1 reveals good stability in rat plasma and rat lung S9 fraction[1].

Trivial name TSLP binder-1
Catalog Number HY-163289
Research Area Inflammation/Immunology
CAS# 2727881-54-9
Purity ≥98.0%
SMILES C[C@@H]1N(C)C([C@@H](NC(C)=O)CSCCC(N2CN3CN(C(CCSC[C@@H](C(N[C@H](C)C(N)=O)=O)NC([C@H](CC4=CC=C(C=C4)F)NC(CNC([C@H](CCCNC(N(C)C)=N)NC([C@H](CC5=CN(C6=C5C=CC=C6)C)NC([C@H](CSCCC3=O)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(C)(C)C)NC([C@H](CC7=CC=CC8=C7C=CC=C8)NC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C2)=O)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/tslp-binder-1.html