SD 0006
SD0006 is an inhibitor of p38 kinase-alpha (p38alpha) with IC50 values of 0.016 μM and 0.677 μM for p38α and p38β. It is selective for p38α kinase over 50 other kinases screened (including p38γ and p38δ with modest selectivity over p38β).
| Trivial name | N/A |
| Catalog Number | S6502 |
| Molecular Formula | C20H20ClN5O2 |
| CAS# | 271576-80-8 |
| Inchi | InChI=1S/C20H20ClN5O2/c21-15-3-1-13(2-4-15)19-18(16-5-8-22-12-23-16)20(25-24-19)14-6-9-26(10-7-14)17(28)11-27/h1-5,8,12,14,27H,6-7,9-11H2,(H,24,25) |
| Inchi Key | CATQHDWESBRRQA-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1C2=C(C(=NN2)C3=CC=C(C=C3)Cl)C4=NC=NC=C4)C(=O)CO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sd-0006.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sd-0006-chemical-structure-s6502.gif |