Cobicistat-d8 | MedChemExpress (MCE)
Cobicistat-d8 (GS-9350-d8) is a deuterated version of Cobicistat (HY-10493). Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) with IC50 values of 30-285 nM. Cobicistat is a pharmacokinetic enhancer that enhances the absorption of anti-HIV active molecules[1][2][3].
| Trivial name | Cobicistat-d8 |
| Catalog Number | HY-10493S |
| Alternative Name(s) | GS-9350-d8 |
| Research Area | Infection |
| CAS# | 2699607-48-0 |
| Purity | ≥98.0% |
| SMILES | CN(CC1=CSC(C(C)C)=N1)C(N[C@H](C(N[C@H](CC[C@H](CC2=CC=CC=C2)NC(OCC3=CN=CS3)=O)CC4=CC=CC=C4)=O)CCN5C([2H])(C([2H])(OC([2H])(C5([2H])[2H])[2H])[2H])[2H])=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/cobicistat-d8.html |