PFI-6
PFI-6 is a selective MLLT1/3 probe that targets the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) with IC50 values of 140 nM and 160 nM for MLLT1 and MLLT3, respectively. PFI-6 demonstrates increased affinity and selectivity for MLLT1/3 than other human YEATS domain proteins (YEATS2/4).
Catalog Number | E4657 |
Molecular Formula | C24H28N8O2 |
CAS# | 2675452-91-0 |
SMILES | C1CN(CCC1CC#N)C2=NC3=C(C(=O)NN=C3)C(=N2)NC4=CC=C(C=C4)N5CCC(CC5)O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/pfi-6.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4657-PFI-6-chemical-structure.png |