PFI-6
PFI-6 is a selective MLLT1/3 probe that targets the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) with IC50 values of 140 nM and 160 nM for MLLT1 and MLLT3, respectively. PFI-6 demonstrates increased affinity and selectivity for MLLT1/3 than other human YEATS domain proteins (YEATS2/4).
Catalog Number | E4657 |
Molecular Formula | C27H29N3O6 |
CAS# | 2675452-91-0 |
SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC2CCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/pfi-6.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4657-PFI-6-chemical-structure.png |