Canertinib (CI-1033)
Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.
Trivial name | PD183805 |
Catalog Number | S1019 |
Molecular Formula | C24H25ClFN5O3 |
CAS# | 267243-28-7 |
Inchi | InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29) |
Inchi Key | OMZCMEYTWSXEPZ-UHFFFAOYSA-N |
SMILES | C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/CI-1033(Canertinib).html |
Additional Information | https://file.selleck.cn/downloads/struct/CI-1033-Canertinib-chemical-structure-S1019.gif |