Zotepine

Zotepine is a 5-HT2A receptor and dopamine D2 receptor antagonist (Ki = 0.69 and 2.3 nM, respectively) used as an atypical antipsychotic for the treatment of schizophrenia. Zotepine also exhibits an antagonistic effect at histamine H1 receptor (IC50 = 8.0 nM).

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Catalog Number 26615-21-4
Alternative Name(s) 2-[(8-Chlorodibenzo(Z)[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine; Nipolept; Lodopin; Zoleptil; Zotepina
Molecular Formula C18H18ClNOS
CAS# 26615-21-4
Purity ≥99%
Inchi InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
Inchi Key HDOZVRUNCMBHFH-UHFFFAOYSA-N
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Supplier Page https://www.bocsci.com/zotepine-cas-26615-21-4-item-64600.html