KT-413

KT-413 (IRAK degrader-1, zomiradomide) is a dual-function PROTAC molecule and a potent degrader of interleukin-1 receptor associated kinase 4 (IRAK4) and the transcription factors Ikaros and Aiolos by acting as both a heterobifunctional degrader and a molecular glue. It can be used in research for developing therapies targeting the activated B-cell (ABC) subtype of diffuse large B-cell lymphoma (DLBCL).

Price Not Available 100mg KT-413 Supplier Page
Trivial name IRAK degrader-1, zomiradomide
Catalog Number E4669
Molecular Formula C43H49NO18
CAS# 2655656-99-6
SMILES CC1CCC2=C(C=CC=N2)C(=O)OCC3(C4C(C(C5(C(C(C(C(C5(C4OC(=O)C)O3)(C)O)OC1=O)OC(=O)C6=CC=CC=C6)OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C)C
Size 100mg
Supplier Page http://www.selleckchem.com/products/kt-413.html
Additional Information https://file.selleck.cn/downloads/struct/E4669-KT-413-chemical-structure.png