NX-5948

A PROTAC that drives BTK degradation

Price Not Available 25 mg NX-5948 Supplier Page
Catalog Number 43484
Research Area Product Type|Biochemicals|PROTACs||Research Area|Cancer|Cell Signaling||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System
Molecular Formula C42H54N12O5
CAS# 2649400-34-8
Purity ≥98%
Inchi InChI=1S/C42H54N12O5/c1-50-21-22-54(42(50)59)32-3-2-16-53(26-32)35-24-45-37(38(43)56)39(48-35)46-30-6-4-28(5-7-30)29-14-17-51(18-15-29)25-27-12-19-52(20-13-27)31-8-9-33(44-23-31)40(57)47-34-10-11-36(55)49-41(34)58/h4-9,23-24,27,29,32,34H,2-3,10-22,25-26H2,1H3,(H2,43,56)(H,46,48)(H,47,57)(H,49,55,58)/t32-,34+/m1/s1
Inchi Key HPTPDBYCFHFWJG-CWTKIQHKSA-N
SMILES NC(C1=C(N=C(N2C[C@H](N3C(N(CC3)C)=O)CCC2)C=N1)NC4=CC=C(C5CCN(CC5)CC6CCN(C7=CN=C(C=C7)C(N[C@H]8CCC(NC8=O)=O)=O)CC6)C=C4)=O
Size 25 mg
Supplier Page https://www.caymanchem.com/product/43484