GS-621763
GS-621763, an orally bioavailable prodrug of GS-441524, shows a dose-dependent antiviral effect on SARS-CoV-2 reporter virus expressing nanoluciferase (SARS-CoV-2 nLUC) replication with an EC50 of 2.8 μM, also inhibits reporter SARS-CoV-2 expressing firefly luciferase (SARS-CoV-2 Fluc) replication with EC50 of 0.125 μM.
Trivial name | N/A |
Catalog Number | E1112 |
Molecular Formula | C24H31N5O7 |
CAS# | 2647442-13-3 |
SMILES | CC(C)C(=O)OCC1OC(C#N)(C(OC(=O)C(C)C)C1OC(=O)C(C)C)C2=CC=C3[N]2N=CN=C3N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/gs-621763.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1112-gs-621763-chemical-structure.gif |