SB415286
SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β. SB415286 causes MM cell growth arrest and apoptosis.
| Trivial name | N/A |
| Catalog Number | S2729 |
| Molecular Formula | C27H24FN7O3 |
| CAS# | 264218-23-7 |
| Inchi | InChI=1S/C27H24FN7O3/c1-27(2,3)21-14-22(35(34-21)16-7-5-4-6-8-16)32-26(37)31-19-10-9-17(13-18(19)28)38-20-11-12-29-25-24(20)30-15-23(36)33-25/h4-15H,1-3H3,(H,29,33,36)(H2,31,32,37) |
| Inchi Key | KYYKGSDLXXKQCR-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C(=NC=C3)NC(=O)C=N4)F)C5=CC=CC=C5 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/sb-415286.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB415286-chemical-structure-s2729.gif |