RMC-6291
A covalent KRASG12C inhibitor
| Catalog Number | 42174 |
| Research Area | Product Type|Biochemicals|Small Molecule Inhibitors|GTPases||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|GTPases |
| Molecular Formula | C55H78FN9O8 |
| CAS# | 2641998-63-0 |
| Purity | ≥98% |
| Inchi | InChI=1S/C55H78FN9O8/c1-13-64-44-19-18-37-30-40(44)41(48(64)39-16-14-24-57-46(39)36(4)71-12)32-53(5,6)34-73-51(69)42-17-15-25-65(59-42)50(68)43(31-38-33-63(37)28-29-72-38)58-49(67)47(35(2)3)61(11)52(70)55(56)22-26-62(27-23-55)45(66)20-21-54(7,8)60(9)10/h14,16,18-19,24,30,35-36,38,42-43,47,59H,13,15,17,22-23,25-29,31-34H2,1-12H3,(H,58,67)/t36-,38-,42-,43-,47-/m0/s1 |
| Inchi Key | HJNFYLSFWYRSHS-CMZSUCOPSA-N |
| SMILES | O=C([C@H](CCC1)NN1C([C@H](C[C@H]2CN3CCO2)NC([C@H](C(C)C)N(C)C(C4(F)CCN(C(C#CC(C)(C)N(C)C)=O)CC4)=O)=O)=O)OCC(C)(C)CC5=[C@@]([C@@]6=C([C@H](C)OC)N=CC=C6)N(CC)C7=C5C=C3C=C7 |
| Size | 5 mg |
| Supplier Page | https://www.caymanchem.com/product/42174 |