Zanapezil fumarate | MedChemExpress (MCE)
Zanapezil (TAK-147) fumarate is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor. Zanapezil fumarate shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex (IC50=51.2 nM). Zanapezil fumarate shows a moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. Zanapezil fumarate can be used for the research of early stages of Alzheimer’s disease (AD)[1][2].
Trivial name | Zanapezil fumarate |
Catalog Number | HY-19651B |
Alternative Name(s) | TAK-147 fumarate |
Research Area | Neurological Disease |
CAS# | 263248-42-6 |
Purity | ≥98.00% |
SMILES | OC(/C=C/C(O)=O)=O.O=C(C1=CC=C(CCCCN2)C2=C1)CCC3CCN(CC3)CC4=CC=CC=C4.[x] |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/zanapezil-fumarate.html |