Wu-5
Wu-5 is an inhibitor of USP10 that blocks its activity in vitro with an IC50 of 8.3 µM. It also promotes FLT3-ITD degradation and synergistically enhances crenolanib-induced apoptosis.
| Catalog Number | E5945 |
| Molecular Formula | C16H21NO3 |
| CAS# | 2630378-05-9 |
| Inchi | InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) |
| Inchi Key | HJORMJIFDVBMOB-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/wu-5.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5945-Wu-5-chemical-structure.png |