ATN 161
ATN-161 is a novel peptide antagonist of integrin α5β1. ATN-161 selectively binds to and blocks the receptor for integrin α5β1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, angiogenesis, and tumor progression. It has potential antineoplastic activity.
| Catalog Number | R0965 |
| Alternative Name(s) | ATN161, ATN 161, ATN-161, AcPHSCNNH2 |
| Molecular Formula | C23H35N9O8S |
| CAS# | 262438-43-7 |
| Purity | >98% |
| Inchi | InChI=1S/C23H35N9O8S/c1-11(34)32-4-2-3-17(32)23(40)29-14(5-12-7-26-10-27-12)20(37)30-15(8-33)21(38)31-16(9-41)22(39)28-13(19(25)36)6-18(24)35/h7,10,13-17,33,41H,2-6,8-9H2,1H3,(H2,24,35)(H2,25,36)(H,26,27)(H,28,39)(H,29,40)(H,30,37)(H,31,38)/t13-,14-,15-,16-,17-/m0/s1 |
| Inchi Key | MMHDBUJXLOFTLC-WOYTXXSLSA-N |
| SMILES | CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)N |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/atn-161-item-r0965-34767.html |