LM-4108 | MedChemExpress (MCE)
LM-4108 (N-(2-Phenylethyl)-indomethacin amide) is a selective and orally active COX-2 inhibitor with an IC50 of 0.06 μM for purified human COX-2. LM-4108 shows anti-inflammatory activity and may be effective in prevention of cancer. Half-lives for the disappearance of 10 μM LM-4108 in rat, human, and mouse liver microsomes were 11 min, 21 min, and 51 min, respectively[1].
| Trivial name | LM-4108 |
| Catalog Number | HY-123639 |
| Alternative Name(s) | N-(2-Phenylethyl)-indomethacin amide |
| Research Area | Inflammation/Immunology; Cancer |
| CAS# | 261766-32-9 |
| Purity | ≥98.00% |
| SMILES | O=C(N1C2=C(C(CC(NCCC3=CC=CC=C3)=O)=C1C)C=C(OC)C=C2)C4=CC=C(C=C4)Cl |
| PubChem Chemical Structure ID | 4292 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lm-4108.html |