ART899
ART899, a derivative of ART558 is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM. It specifically radiosensitizes tumor cells and have a potent stand-alone antitumor effect in cancer cells.
| Catalog Number | E1939 |
| CAS# | 2607139-85-3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/art899.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1939-ART899-chemical-structure.png |