GI254023X
GI254023X (GI 4023, SRI028594) is a selective inhibitor of ADAM10 with 100-fold selectivity for ADAM10 over ADAM17. The IC50 values for recombinant ADAM10 amd ADAM17 are 5.3 nM and 541 nM, respectively.GI254023X can inhibit MMP9.
| Trivial name | GI 4023, SRI028594 |
| Catalog Number | S8660 |
| Molecular Formula | C21H33N3O4 |
| CAS# | 260264-93-5 |
| Inchi | InChI=1S/C21H33N3O4/c1-15(24(28)14-25)17(13-9-12-16-10-7-6-8-11-16)19(26)23-18(20(27)22-5)21(2,3)4/h6-8,10-11,14-15,17-18,28H,9,12-13H2,1-5H3,(H,22,27)(H,23,26)/t15-,17+,18+/m0/s1 |
| Inchi Key | GHVMTHKJUAOZJP-CGTJXYLNSA-N |
| SMILES | CC(C(CCCC1=CC=CC=C1)C(=O)NC(C(=O)NC)C(C)(C)C)N(C=O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gi254023x.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gi254023x-chemical-structure-s8660.gif |