XRD-0394 | MedChemExpress (MCE)
XRD-0394 is a potent and specific dual inhibitor of ATM and DNA-PKcs with oral activity. XRD-0394 significantly enhances tumor cell killing in vitro and in vivo under therapeutic ionizing radiation conditions. In addition, XRD-0394 can potentiate the effects of PARP and topoisomerase I inhibitors in vitro[1].
| Trivial name | XRD-0394 |
| Catalog Number | HY-162472 |
| Research Area | Cancer |
| CAS# | 2595308-10-2 |
| Purity | ≥98.0% |
| SMILES | O=C(C12CCC2)N(C)C3=C1C4=CC(C5=CN=C(OCCNC(C)C)C(NS(C)(=O)=O)=C5)=C(F)C=C4N=C3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/xrd-0394.html |