Pelitinib (EKB-569)
Pelitinib (EKB-569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. Pelitinib (EKB-569) also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282 nM, 800 nM and 1255 nM, respectively. Phase2.
Trivial name | N/A |
Catalog Number | S1392 |
Molecular Formula | C20H23ClFNO |
CAS# | 257933-82-7 |
Inchi | InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2 |
Inchi Key | GGUSQTSTQSHJAH-UHFFFAOYSA-N |
SMILES | C1CN(CCC1CC2=CC=C(C=C2)F)CC(C3=CC=C(C=C3)Cl)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/Pelitinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/Pelitinib-EKB-569-chemical-structure-S1392.gif |