Pelitinib (EKB-569)

Pelitinib (EKB-569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. Pelitinib (EKB-569) also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282 nM, 800 nM and 1255 nM, respectively. Phase2.

Price Not Available 25mg Pelitinib (EKB-569) Supplier Page

Trivial name	N/A
Catalog Number	S1392
Molecular Formula	C24H23ClFN5O2
CAS#	257933-82-7
Inchi	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+
Inchi Key	WVUNYSQLFKLYNI-AATRIKPKSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C
Size	25mg
Supplier Page	http://www.selleckchem.com/products/Pelitinib.html
Additional Information	https://file.selleck.cn/downloads/struct/Pelitinib-EKB-569-chemical-structure-S1392.gif