CL075
CL075 (3M002) is a selective agonist of TLR8 with immunomodulatory properties. It primes human neutrophils by activating signaling pathways, including p47phox phosphorylation and p38MAPK, leading to enhanced reactive oxygen species (ROS) production and contributing to immune defense.
| Trivial name | 3M002 |
| Catalog Number | E5909 |
| Molecular Formula | C10H12N2O4 |
| CAS# | 256922-53-9 |
| Inchi | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 |
| Inchi Key | XNKLLVCARDGLGL-JGVFFNPUSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cl075.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5909-CL075-chemical-structure.png |