MG-1102 | MedChemExpress (MCE)
MG-1102 is first-in-class dual binder of monomeric tau and pre-miRNA-146a. MG-1102 shows specific inhibition of miRNA146a with IC50s of 0.21 mM and 0.36 mM specific inhibition of doublelabeled pre-miRNA146a and mono-labeled pre-miRNA146a, respectively. MG-1102 interacts with tau monomers with a Kd of 3.21 mM by surface plasmon resonance (SPR). MG-1102 is a potential multi-target-directed ligands (MTDLs) for Alzheimer’s disease (AD)[1].
| Trivial name | MG-1102 |
| Catalog Number | HY-160481 |
| Research Area | Neurological Disease |
| CAS# | 2567913-75-9 |
| Purity | ≥98.0% |
| SMILES | COC1=CC(C=CC(C2=NNC=C2CN3C=CC=C3C4=NC=CS4)=C5)=C5C=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/mg-1102.html |