MNK1/2-IN-7 | MedChemExpress (MCE)
MNK1/2-IN-7 (compound 20j) is an orally available inhibitor of MNK1/2 with anticancer activity and hERG safety. MNK1/2-IN-7 also inhibits the phosphorylation of eIF4E, inhibiting the MNK/eIF4E signaling pathway and cancer cell proliferation. MNK1/2-IN-7 is synergistic with Ibrutinib (HY-109970).[15][1].
| Trivial name | MNK1/2-IN-7 |
| Catalog Number | HY-163479 |
| Research Area | Cancer |
| CAS# | 2548283-27-6 |
| Purity | ≥98.0% |
| SMILES | O=C(C1=CC=C(C(C=C2)=NN3C2=NC=C3C4=CC5=C(O4)C=CC=C5)C=C1)N6CCC(CC6)N7CCCCC7 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/mnk1-2-in-7.html |