CHIR-98014
CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Trivial name | CT98014 |
Catalog Number | S2745 |
Molecular Formula | C10H13N5O3S |
CAS# | 252935-94-7 |
Inchi | InChI=1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5+,6+/m0/s1 |
Inchi Key | SCVJRXQHFJXZFZ-KVQBGUIXSA-N |
SMILES | C1C(C(OC1N2C=NC3=C2NC(=NC3=S)N)CO)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/chir-98014.html |
Additional Information | https://file.selleck.cn/downloads/struct/CHIR-98014-chemical-structure-s2745.gif |