CHIR-98014
CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
| Trivial name | CT98014 |
| Catalog Number | S2745 |
| Molecular Formula | C20H17Cl2N9O2 |
| CAS# | 252935-94-7 |
| Inchi | InChI=1S/C20H17Cl2N9O2/c21-12-1-2-13(14(22)9-12)18-16(30-8-7-24-11-30)10-27-20(29-18)26-6-5-25-17-4-3-15(31(32)33)19(23)28-17/h1-4,7-11H,5-6H2,(H3,23,25,28)(H,26,27,29) |
| Inchi Key | MDZCSIDIPDZWKL-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/chir-98014.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CHIR-98014-chemical-structure-s2745.gif |