CHIR-98014
CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
| Trivial name | CT98014 |
| Catalog Number | S2745 |
| Molecular Formula | C16H19N3S.2CH4O3S |
| CAS# | 252935-94-7 |
| Inchi | InChI=1S/C16H19N3S.2CH4O3S/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;2*1-5(2,3)4/h5-10,17H,1-4H3;2*1H3,(H,2,3,4) |
| Inchi Key | SPCMQFLNOVTUBM-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC2=C(C=C1)NC3=C(S2)C=C(C=C3)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/chir-98014.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CHIR-98014-chemical-structure-s2745.gif |