Laduviglusib (CHIR-99021)

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.

Price Not Available 100mg Laduviglusib (CHIR-99021) Supplier Page

Trivial name	CT99021
Catalog Number	S1263
Molecular Formula	C12H19NO2
CAS#	252917-06-9
Inchi	InChI=1S/C12H19NO2/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15)/t9-,10-,12-/m1/s1
Inchi Key	FTBQORVNHOIASH-CKYFFXLPSA-N
SMILES	CCC1=CC2C(C1)CC2(CC(=O)O)CN
Size	100mg
Supplier Page	http://www.selleckchem.com/products/CHIR-99021.html
Additional Information	https://file.selleck.cn/downloads/struct/CHIR99021-chemical-structure-s1263.gif