Orantinib (SU6668)

Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.

Price Not Available 10mM/1mL Orantinib (SU6668) Supplier Page

Trivial name	TSU-68
Catalog Number	S1470
Molecular Formula	C32H39N7O4
CAS#	252916-29-3
Inchi	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35, 36)
Inchi Key	AZSRSNUQCUDCGG-UHFFFAOYSA-N
SMILES	CC(C)OC(=O)C1=CN=C(N=C1C2=CN(C3=CC=CC=C32)C)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/TSU-68(SU6668).html
Additional Information	https://file.selleck.cn/downloads/struct/TSU-68-SU6668-chemical-structure-S1470.gif