LC-2 epimer | MedChemExpress (MCE)
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849[1].
| Trivial name | LC-2 epimer |
| Catalog Number | HY-137516A |
| Research Area | Cancer |
| CAS# | 2502156-12-7 |
| Purity | ≥98.00% |
| SMILES | O=C(N1[C@@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)[C@H](C(C)(C)C)NC(CCOCCCN(CCC4)[C@@H]4COC5=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C7C(CN(C8=CC=CC9=C8C(Cl)=CC=C9)CC7)=N5)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lc-2-epimer.html |