SB-334867 hydrochloride
SB-334867 hydrochloride (SB 334867A) is an excellent,selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.
Trivial name | SB 334867A |
Catalog Number | E7599 |
Molecular Formula | C2H7NO3S |
CAS# | 249889-64-3 |
Inchi | InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6) |
Inchi Key | XOAAWQZATWQOTB-UHFFFAOYSA-N |
SMILES | C(CS(=O)(=O)O)N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/sb-334867-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7599-sb-334867-chemical-structure-tube.png |