GMB-475

GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.

Price Not Available 10mM/1mL GMB-475 Supplier Page

Trivial name	N/A
Catalog Number	S8888
Molecular Formula	C43H46F3N7O7S
CAS#	2490599-18-1
SMILES	CC1=C(SC=N1)C2=CC=C(CNC(=O)C3CC(O)CN3C(=O)C(NC(=O)COCCOC4=CC=C(C=C4)C5=CC(=NC=N5)NC6=CC=C(OC(F)(F)F)C=C6)C(C)(C)C)C=C2
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/gmb-475.html
Additional Information	https://file.selleck.cn/downloads/struct/gmb-475-chemical-structure-s8888.gif