GSK046 (iBET-BD2)
GSK046 (iBET-BD2) is a selective and orally active inhibitor of BET (bromodomain and extraterminal domain) with IC50 of 264 nM, 98 nM, 49 nM and 214 nM for BRD2BD2, BRD3BD2, BRD4BD2 and BRDTBD2, respectively. GSK046 exhibits immunomodulatory activity.
| Catalog Number | S9684 |
| Molecular Formula | C23H27FN2O4 |
| CAS# | 2474876-09-8 |
| SMILES | CC(OC1=CC(=CC(=C1NC(C)=O)F)C(=O)NC2CCC(O)CC2)C3=CC=CC=C3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gsk046.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s9684-gsk046-chemical-structure.gif |