Dapivirine (TMC120)
Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.
Trivial name | N/A |
Catalog Number | S2914 |
Molecular Formula | C20H19N5 |
CAS# | 244767-67-7 |
Inchi | InChI=1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25) |
Inchi Key | ILAYIAGXTHKHNT-UHFFFAOYSA-N |
SMILES | CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/dapivirine.html |
Additional Information | https://file.selleck.cn/downloads/struct/Dapivirine-chemical-structure-s2914.jpg |