Doxorubicinone
Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.
| Trivial name | Adriamycin aglycone, Adriamycinone |
| Catalog Number | E7831 |
| Molecular Formula | C14H14ClFN8 |
| CAS# | 24385-10-2 |
| Inchi | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1 |
| Inchi Key | PDOQBOJDRPLBQU-QMMMGPOBSA-N |
| SMILES | CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/doxorubicinone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7831-doxorubicinone-chemical-structure-tube.png |