Aβ42-IN-1 free base
Aβ42-IN-1 free base (compound 1v) is an orally active, high brain exposure γ-secretase modulator. Aβ42-IN-1 free base potently reduces Aβ42 levels with an IC 50 value of 0.091 μM, and significantly reduces brain Aβ42 levels in mice. Therefore, Aβ42-IN-1 free base is a promising disease-modifying compound for the treatment of Alzheimer’s disease [1].
| Catalog Number | T10443 |
| Research Area | Others |
| Molecular Formula | C29H26N4O2 |
| CAS# | 2434633-17-5 |
| SMILES | O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=CC=C5)C=C4)=CC=CN32)C=C1)NCC |
| Size | 50 mg |
| Supplier Page | https://www.targetmol.com/compound/Aβ42-IN-1 free base |
| Additional Information | https://www.targetmol.com/datasheet/T10443 |