KT474
A PROTAC that drives IRAK4 degradation
| Catalog Number | 41053 |
| Alternative Name(s) | SAR444656 |
| Research Area | Product Type|Biochemicals|PROTACs||Research Area|Cell Biology|Cell Signaling||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Innate Immunity |
| Molecular Formula | C44H49F2N11O6 |
| CAS# | 2432994-31-3 |
| Purity | ≥95% |
| Inchi | InChI=1S/C44H49F2N11O6/c1-52-39-27(4-2-6-34(39)57(44(52)61)35-11-12-37(58)50-43(35)60)5-3-19-62-30-13-16-53(17-14-30)22-26-7-9-28(10-8-26)56-24-33(38(51-56)40(45)46)48-42(59)32-21-47-55-18-15-36(49-41(32)55)54-23-31-20-29(54)25-63-31/h2,4,6,15,18,21,24,26,28-31,35,40H,7-14,16-17,19-20,22-23,25H2,1H3,(H,48,59)(H,50,58,60)/t26-,28-,29-,31-,35?/m1/s1 |
| Inchi Key | NQGKNAVUMAHSQN-KDRPOVOJSA-N |
| SMILES | O=C1N(C(CCC2=O)C(N2)=O)C3=CC=CC(C#CCOC(CC4)CCN4C[C@H]5CC[C@H](N(N=C6C(F)F)C=C6NC(C7=C(N=C(N8[C@@]9([H])CO[C@@]([H])(C8)C9)C=C%10)N%10N=C7)=O)CC5)=C3N1C |
| Size | 10 mg |
| Supplier Page | https://www.caymanchem.com/product/41053 |