Anticancer agent 199 | MedChemExpress (MCE)
Anticancer agent 199 (Compound G-4) induces apoptosis in triple negative breast cancer (TNBC) cells via the mitochondrial pathway through inhibiting EGFR, AKT and MAPK pathways. Anticancer agent 199 also induces Ferroptosis by down-regulating LCN2. Anticancer agent 199 inhibits TNBC cell viability and migration, and induces S phase cell cycle arrest. Anticancer agent 199 is a derivate of cyclin-dependent kinase inhibitor Rocovitine[1].
| Trivial name | Anticancer agent 199 |
| Catalog Number | HY-158049 |
| Research Area | Cancer |
| CAS# | 2422001-24-7 |
| Purity | ≥98.0% |
| SMILES | OCCN1CCC(CC1)C2CCN(CC2)C3=NC4=C(C(NCC5=CC=C(C(F)=C5)Cl)=N3)N=CN4C6CCCC6 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/anticancer-agent-199.html |